Brian King, deputy director for research translation at the CDC Office on Smoking and Health, said in the release
Specific Concerns with Inhaling Pipe Tobacco Pipe tobacco presents unique risks when inhaled: Higher particulate matter: The coarser cut and aromatic additives create more particulates when burned Different chemical profile: Flavoring agents and humectants add compounds not found in cigarette tobacco Increased tar exposure: Some pipe tobaccos produce higher tar levels when combusted Respiratory irritation: The harshness indicates tissue inflammation, a precursor to disease According to FDA regulations, anyone who manufactures, modifies, mixes, fabricates, assembles, processes, labels, repacks, relabels, or imports tobacco products is considered a tobacco product manufacturer
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The indirect effects were shown by treating airway epithelial cells with CSE: this exposure caused these cells to release IL-1 in a CSE-dose and culture time-dependent manner
